Science Behind CBD
What is CBD?
Cannabidiol, or CBD, is a component of cannabis
Science is proving that CBD has enormous medical and therapeutic potential
CBD is not THC (the component of cannabis that provides the "high")
CBD does not impart a "high"
CBDs analgesic and anti-inflammatory effects make
cannabidoil a good choice for post-workout muscle recovery.*
*Formukong, et al., Analgesic and anti-inflammatory activity of constituents of Cannabis sativa L.; Inflammation. 1988 Aug; 12(4):361-71.
CBDs Anxiolytic qualities
CBDs anxiolytic qualities show promise as a treatment for anxiety,
depression, stress, generalized social anxiety disorder and PTSD.*, **, ***
*Schier, A., et al., Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug. Braz J Psychiatry. 2012 Jun;34 Suppl 1:S104-10.
**Crippa, J., et al., Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. J Psychopharmacol. 2011 Jan;25(1):121-30.
***Rafael M. Bitencourt, et al., Cannabidiol as a Therapeutic Alternative for Post-traumatic Stress Disorder: From Bench Research to Confirmation in Human Trials, Front Neurosci. 2018; 12: 502.
CBD may help keep you moving. A 2017 report concluded that there was substantial evidence that hih-CBD cannabis-based products are effective for treating chronic pain and inflammation.*, **
*National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Population Health and Public Health Practice; Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda. Washington (DC): National Academies Press (US); 2017 Jan 12.
**Wei-Xong, et al., Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors. J Exp Med. 2012 Jun 4; 209(6): 1121–1134.
CBD holds promise for Alzheimer's patients
CBD holds promise in the prevention and treatment of social and object recognition and memory deficits in Alzheimer’s patients.*, **
*Cheng D., et al., Long-term cannabidiol treatment prevents the development of social recognition memory deficits in Alzheimer's disease transgenic mice. J Alzheimers Dis. 2014;42(4):1383-96.
**Cheng D, et al., Chronic cannabidiol treatment improves social and object recognition in double transgenic APPswe/PS1∆E9 mice. Psychopharmacology (Berl). 2014 Aug;231(15):3009-17.
DOES CBD REGULATE SLEEP?
Studies show promising results when using CBD to regulate sleep, wakefulness, and insomnolence.*,**,***
Hortes n Chagas, M et al. (2013). Effects of acute systemic administration of cannabidiol on sleep-wake cycle in rats. Journal of Psychopharmacology, 27(3). Retrieved from: http://journals.sagepub.com/doi/abs/10.1177/0269881112474524
Chagas, MH et al. (2014). Cannabidiol can improve complex sleep-related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson’s disease patients: a case series. Journal of clinical pharmacy and therapeutics, 39(5): 564-6. Retrieved from: https://www.ncbi.nlm.nih.gov/pubmed/24845114
Brooks, PL and JH Peever. (2008). Unraveling the mechanisms of REM Sleep Atonia. Sleep, 31: 1473-91. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579970/
CBD & Childhood-onset Epilepsy
In June, 2018, the US FDA approved Epidolex, a CBD product, for the treatment of 2 severe forms of childhood-onset epilepsy.*